5-Amino-1MQ

5-Amino-1MQ is a small chemical, not a peptide ^[6]. Its full name is 5-amino-1-methylquinolinium ^[6]. FDA's letter names the form used to make drugs: 5-amino-1-methylquinolinium iodide ^[1].

It blocks an enzyme called NNMT ^[9]. An enzyme is a protein that speeds up a chemical step in the body. NNMT has a part in how cells use and store energy ^[7]. Researchers have tested 5-Amino-1MQ in obese mice as a possible drug for obesity ^{[8] [9]}. One lab study tested it on cancer cells ^[10].

5-Amino-1MQ has no approved use in the US: FDA says outsourcing facilities may not use it to make drugs ^[1]. That means no outsourcing facility may lawfully make drugs from it. It does not mean a seller may offer it for people. FDA says drugs one facility made from it lacked FDA approval ^[1]. Checked 26 October 2026.

An outsourcing facility is a compounder of sterile drugs that registers with FDA under section 503B of the law ^{[1] [2]}. It may use a bulk ingredient if the ingredient is on FDA's 503B list. It may also use one to make a drug in short supply ^[1]. FDA says 5-Amino-1MQ meets neither test ^[1].

A regular pharmacy follows section 503A of the law, which has its own three tests ^[3]. FDA's lists for pharmacies and for outsourcing facilities do not name 5-Amino-1MQ ^{[4] [5]}. FDA's pages in our sources do not say whether a pharmacy may use it.

FDA keeps a record of the chemical under an ID code, UNII PMX593N4N3 ^[6]. That code only names the substance. It is not approval.

The evidence grade is animal-only: every study in our sources was in mice or in cells, and none was in people ^{[7] [8] [9] [10]}.

In 2024, researchers gave 5-Amino-1MQ to obese mice on a high-fat diet for 28 days ^[9]. It limited weight and fat gain ^[9]. It also helped the mice control blood sugar and cut fat in the liver ^[9].

In a 2022 study, obese mice were switched to a low-fat diet ^[8]. Mice that also got 5-Amino-1MQ lost more weight and fat than mice on the diet alone ^[8]. Their gut bacteria also changed ^[8].

A 2018 study tested a family of related NNMT blockers ^[7]. In obese mice, a potent one cut weight and body fat ^[7]. The summary does not name that molecule, so this may be evidence about a different chemical ^[7].

In a lab dish, the chemical slowed the growth of cervical cancer cells ^[10]. These are animal and cell results, not results in people.

FDA says outsourcing facilities may not make drugs from 5-Amino-1MQ, and our sources show no approved use ^[1]. There is no legal route to it in the US today that a federal source shows.

Our sources hold no clinical trial of it. Any open trial appears in the trials block below, with the date the official registry was last checked.

One way of getting 5-Amino-1MQ shows up in federal records: an outsourcing facility that made drugs from it although the law does not allow it ^[1]. In July 2025, FDA inspected a Florida outsourcing facility ^[1]. FDA says the facility made drugs from 5-Amino-1MQ, which it may not use ^[1]. In January 2026, FDA sent the facility a warning letter ^[1].

FDA also found that the facility made sterile drugs in unclean conditions ^[1]. FDA noted that the facility had stopped making drugs and recalled its sterile drugs ^[1]. But FDA said the facility gave no proof that it stopped making drugs from 5-Amino-1MQ ^[1]. Our sources hold no federal record of other ways 5-Amino-1MQ reaches people.